Hyperbaric Oxygen Therapy Options for Stroke Recovery
Hyperbaric Oxygen Therapy Options for Stroke Recovery
Stroke prevalence has spurred scientists to develop more effective stroke recovery therapies, including hyperbaric oxygen therapy (HBOT).
Recovery from an ischemic or TIA (“mini stroke”) may not be guaranteed, but this much is clear: people who receive timely and effective treatment recover with fewer post-stroke effects.
Unfortunately, timely treatment is not always attainable:
- Stroke is a “leading cause of death in the United States and is a major cause of serious disability for adults.”
- “More than half of stroke survivors age 65 and older” experience reduced mobility, relegating some individuals to a wheelchair for the remainder of their lives. Many struggle with cognitive function, speech difficulties, and visual impairments as well.
Thankfully, advanced rehabilitation programs exist, including hyperbaric oxygen therapy (HBOT) options and other therapies. The experts at Aviv Clinics discuss these key details below.
What Happens to the Brain during a Stroke?
When a stroke strikes, it immediately starts killing brain cells due to loss of blood flow. As many as two million brain cells die each minute the stroke goes untreated. Other cells become injured but don’t necessarily die off. Neurologists often describe them as being “stunned”.
Still, a significant part of the brain’s real estate comes under attack. The combined damage from injured and necrotic (dead) brain cells results in both immediate and long-term symptoms such as:
- Limb weakness or paralysis
- Slurred speech
- Vision complications
- Balance issues.
Nothing can be done about the dead brain cells, which is why timely intervention is so critical. However, a growing body of research indicates that HBOT can help repair the injured cells, even years after the initial stroke
What Is Hyperbaric Oxygen Therapy (HBOT)?
Hyperbaric oxygen therapy (HBOT) is a type of therapy that uses pressurized chambers to allow individuals to breathe in 100% pure oxygen.
In the hyperbaric suites at Aviv Clinics, the air is pressurized in the HBOT chamber to above atmospheric levels. This environment increases oxygen levels in the body to about 17 times higher than normal, allowing oxygen to be delivered even to damaged cells, such as those injured by stroke.
How Does HBOT Help with the Post-Stroke Recovery Process?
The unique HBOT protocol at Aviv Clinics uses a scientifically validated process in which oxygen levels are fluctuated throughout the HBOT session. When the mask is on, oxygen levels are very high. But, when the mask is off, the body is deceived into sensing a state of “low” oxygen because of the rapid decline.
This fluctuation triggers the body into repair and regeneration mode, which in turn:
- Improves injured cell health
- Builds new blood vessels, optimizing blood flow
- Grows new connections in the brain
In the past, growing those new connections was inconceivable. Scientists previously believed that once neurons were destroyed, they could never rebound. Research has since disproved that notion.
What Benefits Can Stroke Survivors Achieve with HBOT?
Several studies have proven the benefits of using HBOT in post-stroke recovery. Repair mechanisms in the brain, prompted by HBOT, result in:
- Regained speech and reading capabilities
- Restored motor function, even with paresis
- Return to independence in performing daily activities
The Aviv Medical Program
When combined with the exercise, personalized nutrition, and extensive assessments that are part of the Aviv Medical Program, the outcomes become even more impressive:
- Some Aviv clients progress from using wheelchairs to walking on their own or with an assistive device.
- Clients who lost their ability to speak make immense recovery strides.
- Many report that the biggest benefit is simply not being a “burden” on their loved ones.
Our post-stroke program remains focused on research and incorporates a holistic and personalized approach that can include the following:
- In-depth review of health history
- Comprehensive physical exam
- Highly advanced brain imaging scans
- Neurological and neurocognitive tests
- Body composition analysis
- A detailed report of our assessment findings
- Cognitive training
- Physical training
- Dietary coaching
- Hyperbaric oxygen therapy (HBOT)
- A post-treatment report of your improvements and recommendations for future progress
Learn more about the program>>
Even if a person has no visible effects after having a stroke, the brain has still been damaged—and they are at a higher risk for a subsequent stroke. HBOT, through the Aviv Medical Program, can help mitigate that risk by improving the flow of blood to brain tissue and potentially prevent future strokes from occurring.
How Soon after a Stroke Can Hyperbaric Oxygen Therapy Be Administered?
Aviv Clinics recommends a 3-6 month wait after a stroke before beginning the Aviv Medical Program protocols. This allows for the brain’s natural healing progression to take hold.
The sooner stroke survivors act after the post-acute stage, the better. The research our scientists have done indicates a strong cohort from the one-month point to four years post-stroke.
That said, there’s really no limit on how long after a stroke individuals can participate in the program. We’ve seen success in clients who were as many as 10 years into their stroke recovery.
How Long Does It Take to See Results?
Most people see improvement from the Aviv Medical Program within the 8-12 weeks of therapy and medically verifiable results by the end of their treatment.
But keep in mind, no one-size-fits-all approach exists. You’ll receive your own unique therapy plan, so outcomes and timelines vary. Our ability to quantify your health plan is ultimately what delivers results.
For reference, here is a general overview of what our program looks like:
- Step 1: Assessment—A comprehensive set of neurocognitive, physical, and genomic assessments.
- Step 2: Treatment—Based on the assessment, we develop a customized routine that can include hyperbaric oxygen sessions with other types of personalized training/therapies. These may take place over 12 weeks.
- Step 3: Analysis—Our team uses advanced analytics to assess your program’s efficacy, and make the necessary adjustments.
- Step 4: Follow up—The Aviv Clinics team will offer ongoing monitoring and engagement post-treatment to help maintain your results.
Keren Trabelsi Finds Hope after Her Stroke
“[Treatment at Aviv is] like driving a Ferrari on the road to recovery versus driving like an old beaten-up car….”
Keren Trabelsi underwent an ischemic stroke. This caused cognitive issues and paralysis on the left side of her body. Daily tasks grew more difficult, which left her feeling defeated.
Fortunately, Keren found the Aviv Medical Program. Aviv Clinics provided a personalized treatment plan encompassing many of the therapies we outlined earlier.
Thirteen months later, Keren can walk comfortably, type with her left hand again, and engage in a myriad of activities (crossword puzzles, Sudoku, etc.) she couldn’t participate in after her stroke.
The Bottom Line
Stroke survivors no longer need to feel like life is over due to debilitating cognitive and physical impairments. The Aviv Medical Program is rooted in extensive scientific research and has been instrumental in helping stroke survivors thrive well into their golden years.
Contact us to learn more about the Aviv Medical Program and how it can benefit you or a loved one.
Choosing the Right Hyperbaric Oxygen Therapy Program for You
Hyperbaric oxygen therapy (HBOT) has become available for more health conditions to help extend healthspan, improve physical performance, and manage cognitive decline. As more facilities providing HBOT open around the United States, different types of HBOT technology and treatment protocols have appeared. It has become increasingly important to understand the differences and identify the option best able to meet your health goals and needs.
What are the types of hyperbaric oxygen therapy chambers?
There are two types of hyperbaric oxygen therapy chambers: multiplace and monoplace chambers.
Multiplace chambers are large, modern, comfortable rooms that feature cushioned seating. They are designed much like a first class airplane seat, with personal entertainment tablets. Aviv Clinics clients receive their HBOT treatments in spacious multiplace chambers that allow them to sit comfortably and engage in brain training during the course of the session.
Aviv Clinics – Multiplace chamber HBOT suite
Monoplace chambers are rigid glass or plastic tubes that are meant for one person. Patients must use them lying down. Most clinics use monoplace chambers. People who are claustrophobic in small spaces might find them confining. People sometimes associate them with hospital burn units, wound care facilities, or MRI machines. They are sometimes even referred to as “Michael Jackson” tubes because the singer reportedly used this method from time to time.
What treatment program is used for HBOT?
HBOT treatment programs can range widely, so it is important to understand which protocol best fits your health goals. Some facilities offer single, spa-like experiences, while others provide basic HBOT for a few sessions to address specific issues. On the other end of the spectrum are comprehensive, research-backed programs, such as the Aviv Medical Program, that address issues such as mild cognitive decline, stroke, Lyme disease, PTSD and fibromyalgia.
Basic hyperbaric oxygen therapy for specific issues, such as gangrene, non-healing wounds, infections, and “the bends” experienced by some divers, has been used for decades. For these conditions, the number of HBOT treatments can be as few as one or two sessions.
A comprehensive HBOT treatment protocol, like the Aviv Medical Program, addresses issues that affect your healthspan and physical and mental performance. It differs not only because of the length—every client does at least 60, two-hour HBOT “dives” throughout the 12-week program—but also because it encompasses more than just hyperbaric oxygen therapy. Clients receive individualized exercise and nutrition coaching, as well as regular check-ins with a multidisciplinary team of physicians, physiologists, nutritionists, neuropsychologists, and other health professionals.
Be aware of clinics that offer unclear treatment protocols. Some of these facilities promote their services as more of a spa-like experience, with no standardized treatment plans or science-backed evidence to support their claims.
Is the HBOT program backed by research?
Review whether the facility you are considering has developed its treatment protocols based on scientific, peer-reviewed research. Every treatment you choose has the ability to affect your body positively or negatively, so doing your research and choosing a reputable clinic is paramount.
The pressure and length of treatments, as well as the oxygen dosage used in Aviv’s HBOT treatments, are the result of peer-reviewed scientific research. This comprehensive protocol has been shown to maximize the body’s own regenerative power. It is a unique, proprietary system of modulated oxygen exposure that is only offered by Aviv Clinics.
What type of expert/clinician support is available?
An important consideration when choosing your hyperbaric oxygen therapy clinic is the type of expert support available to provide treatment and guidance. The best treatment protocols include a multidisciplinary team.
At Aviv Clinics, clients have access to an expert clinician team that includes physicians, physiologists, psychologists, and nutritionists throughout the 12-week program. The team continues to stay in contact with clients even after the treatment course to ensure they continue their progress. Subsequent six-month follow-up assessments are also part of the program and help clients continue to track their progress.
What assessments are performed?
Tracking progress from the start of the treatment course is needed to confirm whether your health goals were reached. Some clinics include scanning and diagnostic assessments as part of their offerings.
Aviv Clinics offers the industry’s most comprehensive battery of cognitive and physical tests to set a baseline for each client at the start. The Aviv Medical Program assessments include:
- In-depth medical intakes performed by our expert clinical team, including physicians, neuropsychologists, physiologists, physical therapists, and nutritionists
- Full battery of computerized cognitive testing that includes evaluation of your memory, focus, information processing speed, attention, and executive function
- Extensive blood tests
- Advanced MRI brain imaging protocols (anatomical, perfusion, microstructure)
- CPET – a heart and lung performance test to measure how the body produces energy with and without oxygen
- Body composition analysis, including gait, balance, and overall motor functions
- Full genetic sequencing
- Cellular performance tests including a stem cell count and assessment of aging biomarkers such as telomeres, which help to calculate your true biological age
The assessments are repeated at the end of the program. This allows our team to provide clients with a full report, summarizing progress throughout the program, and providing the data and analysis necessary to move forward with health and wellness goals.
Will there be medical support during the HBOT session?
Having professional oversight and support during your HBOT treatment is a critical consideration. At facilities that use small, monoplace tubes, clients are typically monitored through cameras.
At Aviv Clinics, a nurse is present inside the HBOT suite to support clients and ensure appropriate treatment during all hyperbaric dives. A trained technician also monitors the session from outside of the chamber. A physician is on site at all times during treatments as safety is Aviv’s top priority.
Is a comprehensive progress report provided?
Many condition-specific or other facilities work on a session-to-session basis. Even if a long-term recovery plan is the purpose, they may only track progress per HBOT treatment.
Aviv Clinics takes a holistic approach by providing all-encompassing and in-depth reports. After clients complete the Aviv Medical Program, the clinician team provides a detailed before-and-after cognitive and physiological analysis, showing their markers of improvement. Clients review their progress, one-on-one with the physician, who explains and interprets the data, and provides next steps.
The Bottom Line
An HBOT treatment protocol that is backed by research, supported by a multidisciplinary and caring clinician team, and a full range of assessments to show progress are all important considerations for choosing the right HBOT clinic to meet your health goals.
The Aviv Medical Program is rooted in extensive scientific research and trials conducted on HBOT treatment for a variety of conditions, including reversing the signs of biological aging, mild cognitive decline, post-stroke recovery, Lyme disease, PTSD, and fibromyalgia.
Contact us to learn more about the Aviv Medical Program and how it can benefit you.
How Hyperbaric Oxygen Therapy Improves Blood Circulation
Blood circulation is one of the most important functions in our bodies.
Without the circulation system, the brain, heart and other vital organs couldn’t receive the oxygen we need to function properly and survive. Good circulation keeps your mind sharp, your heart strong, and can even give your complexion a youthful flush. It is absolutely vital to staying strong, healthy and energetic throughout your life.
However, the aging process can slow the flow of blood throughout the body. This can cause all manner of health problems and leave you feeling tired, sluggish and weak. Fortunately, there are ways to combat poor circulation caused by the aging process. An innovative treatment protocol based on hyperbaric oxygen therapy (HBOT) has been clinically proven to improve the flow of blood throughout the body, and can even promote the creation of new blood vessels in the brain and other vital organs.
So how does hyperbaric oxygen therapy work to improve blood flow?
How Aging Affects Blood Circulation
As we age, the number of blood vessels in our body naturally decreases. Blood vessels are a critical part of the circulation system through which our organs receive oxygen to work properly. As smaller, tinier blood vessels naturally die off, organs no longer receive as much oxygen as they once did.
For the brain, losing circulation and not getting enough oxygen can mean losing cognitive function. You may experience brain fog or memory problems. It can be small things, such as struggling to remember where you put your keys, to more extensive neurological problems like vascular dementia.
But it’s not just the brain that’s affected by poor circulation. A lack of blood flow can affect every part of the body.
In men, a lack of blood flow can lead to erectile dysfunction or other problems with sexual health. Poor circulation can also lead to tingling or numbness in the hands and feet, muscle cramps, or swelling and pain in the limbs. It can leave you feeling sluggish and sleepy, or even leave your skin dry and discolored due to the lack of oxygen.
So how can you combat the restricted blood flow caused by aging?
Three Ways Hyperbaric Oxygen Therapy Can Help
HBOT improves circulation
At one time, scientists believed that the blood vessels lost to aging were gone forever. New research has revealed otherwise. Studies have demonstrated that Hyperbaric Oxygen Therapy (HBOT) can directly improve blood flow. During an HBOT session, patients breathe 100% oxygen in a high-pressure environment, like the cutting-edge HBOT suite at Aviv Clinics.
If the HBOT is delivered using a specific protocol, the increased levels of oxygen in the body can promote a process called “angiogenesis”. Angiogenesis is the growth of new capillary blood vessels in the body. This process increases blood flow in the body, helping deliver vital oxygen to organs that have been slowed by age. Angiogenesis can rejuvenate and repair your body, and the scientifically proven benefits are promising.
HBOT helps enhance cognitive health
Because angiogenesis rebuilds blood vessels, it directly promotes improved circulation in all parts of the body. In the brain, improved circulation means better cognitive function.
HBOT was shown to directly benefit the cognitive performance of patients who had all suffered a stroke 3-36 months before the research study and had at least one motor dysfunction. Patients who received a two-month protocol of HBOT treatment experienced significant improvements to their neurological functions. In some of the most dramatic results, patients regained their ability to speak, their ability to read and write, and some even regained function in paretic limbs.
It’s not just stroke patients that can benefit from angiogenesis. More studies reveal how increased blood flow in the brain can improve the lives of healthy older adults. SPECT imaging scans of patient’s brains before and after HBOT treatment reveal significant improvements to cerebral blood flow and improved function in different areas of the brain.
The results? These improvements directly correlate to increased attention spans, higher information processing speed, and improved executive function.
HBOT benefits overall wellness
The angiogenesis brought on by HBOT can help more than just your brain. Angiogenesis can benefit your entire body. Having good circulation can increase energy levels and leave you feeling more youthful and active. You may find yourself up for more vigorous physical activities outside…or even behind closed doors! HBOT has been shown to help male patients that suffer from erectile dysfunction.
In this study, thirty men who suffered from ED saw significant positive outcomes thanks to the increased blood flow from angiogenesis. The men, who averaged around 59 years of age, all reported greater overall sexual satisfaction after undergoing HBOT. Women can also benefit from improved circulation, since female arousal and sexual satisfaction depend on proper blood flow.
Other benefits of having good circulation can include faster wound healing and more youthful-looking skin, since angiogenesis promotes tissue regeneration. Good blood flow affects every aspect of your life, keeping you healthy and strong. Undergoing HBOT programs, like those at Aviv Clinics, can directly promote good circulation throughout the whole body.
The Unique HBOT Protocol at Aviv Clinics
While HBOT can produce amazing results on its own, it’s only half the battle. At Aviv Clinics, we emphasize the importance of treating the whole body. Having a poor diet and living a sedentary lifestyle can contribute to poor circulation and worsen the effects of aging. In order for the benefits of HBOT to last, healthy diet and exercise regimens must be followed. Think of it as doing maintenance on a car after undergoing an extensive series of repairs. We want you to be able to enjoy the benefits of your treatment for years to come. This is why our clients are supported by a multidisciplinary team of professionals from all areas of expertise.
The Aviv Clinics 12-week program begins with an in-depth analysis of your current physical state carried out by our team of experts. We use the extensive data collected during this time to formulate a customized treatment plan based on your biggest areas of concern. You’ll be paired with a dietician and a physiologist who will formulate custom diet and exercise regimens tailor-made to your goals. You’ll learn all about the importance of proper nutrition and how to promote good circulation. By the end of the twelve weeks, you’ll be well-equipped with the tools you need to keep the benefits of good circulation throughout your life. But our relationship with you doesn’t end after twelve weeks are up.
We’ll keep in touch with you even after the program has ended. Every six months, you’ll be invited back to our clinic for a day of physical assessment to monitor your progress. You’ll be able to see exactly how far you’ve come since you began. And you’ll understand exactly how good circulation can benefit every aspect of your life.
Contact us to learn more about the Aviv Medical Program and how it can benefit you!
Rehabilitation Options, Including Hyperbaric Oxygen Therapy (HBOT), for Stroke Patients
Strokes are “a leading cause of serious long-term disability” in the United States. Given that “87% of all strokes are ischemic” or caused by artery or vein blockage, it makes sense that most patients suffer long-term functional impairments.
These impairments can range from paralysis, speech difficulties, and sensory issues to a host of other cognitive dysfunctions. Additionally, many stroke patients have had a stroke before—“nearly 1 in 4” survivors have suffered at least one stroke previoulsy.
Rest assured, multiple rehabilitation options are available for stroke patients, including hyperbaric oxygen therapy (HBOT). We dive into the key details below.
Remember that each person’s medical condition and background are entirely unique. Thus, speaking with a physician about treatment options is essential to getting back to optimal health.
What Are the 3 Common Stroke Relief Options?
Stroke relief generally entails working with a diverse medical team of physicians, nurses, and therapists. This support team may recommend one or more of the following options:
- Speech therapy: Stroke patients can experience speech challenges, ranging from slurred world to significan difficulties with oral communicationor understanding people (aphasia). This is due to damage to the “left side of the brain that controls speech and language.” Cases like this often merit speech therapy.
Patients work with speech-language pathologists (SLPs) to relearn techniques such as:
- Controlling mouth and throat muscles to speak more clearly and adequately swallow
- Participating in cognitive language exercises to restore communication and comprehension skills
Research illustrates early speech intervention with aphasia patients “had a massive increase in their ability to communicate at 12 and 26 weeks after their stroke.” Patients could speak better and exhibited less difficulty finding and using the right words.
- Physical therapy: A physical therapist (PT) engages patients in movement exercises to help them reacquire motor skills. PTs generally help stroke patients relearn activities such as walking, sitting, standing, and switching from one movement to another.
Medical experts believe consistent PT lowers “risks of hospital readmission within a month after discharge” because it helps patients:
- Restore movement and accomplish tasks
- Plan for the next step of post-acute care (e.g., patient rehab facility, skilled nursing facility, or home care assistance)
- Occupational therapy: Occupational therapists help patients carry out everyday activities. They aim to help stroke patients live as independently as they can. OTs work with post-stroke patients to assess how the stroke has affected their lifestyle.
For those who have difficulties dressing, cooking, or bathing, the OT will find solutions to help carry out these activities of daily living to the best of their ability. These statistics outline the importance of OT in the recovery process.
- One study of Medicare claims data found that “Rehabilitation services including physical therapy and occupational therapy play important roles in promoting functional recovery and preventing deconditioning during acute hospitalizations.” However, “Only 61% of patients with ischemic stroke received both physical therapy and occupational therapy services in the acute setting.”
- One study notes that patients who participated in OT programs focused on impairment and basic living activities “progressed to more advanced activities over time (e.g., less bed mobility, more home management).”
- Research indicates the key to succeeding in a post-stroke treatment plan is “well-focused, repetitive practice.” The more patients practice, the more they will succeed in getting back to optimal health.
The Groundbreaking Therapeutic Approach of HBOT
An up-and-coming therapy for long-term stroke recovery that has shown promise in clinical research is Hyperbaric Oxygen Therapy (HBOT). HBOT has clear indications of brain-cell rehabilitation in patients suffering from post-stroke disabilities.
HBOT and its apparent benefits for post-stroke patients were studied and reviewed in an article published in the peer-reviewed journal PLOS One:
- The participants were exposed to a unique protocol, including daily HBOT sessions over two months. All the patients showed improved neurological functioning, indicating “that HBOT can lead to significant neurological improvements in post stroke patients even at chronic late stages.”
- Noticeable recovery included “regained speech (almost fluent) and reading capabilities.” Even in patients with less dramatic results, everyday tasks like bathing and dressing became possible unaided by the end of the treatment period.
- Patients were further assessed using brain metabolism imaging (SPECT scans) to examine brain activity during the HBOT treatment. “The SPECT after HBOT demonstrated the disappearance of the perfusion lesions.”
- The study indicated a link between oxygen and stroke—“increasing the plasma oxygen concentration with hyperbaric oxygenation is a potent means of delivering to the brain sufficient oxygen for tissue repair.”
Not only did the study determine significant improvements in patients treated with HBOT, it crucially found that the progression occurred in patients even many months after the stroke event.
The study’s objective was to “evaluate the effects of HBOT started in the late-chronic phase after the acute stroke.” All the patients experienced strokes between six and 36 months prior to the HBOT treatment.
The Aviv Medical Program: The Road to a Better Life
Backed by over a decade of research, the Aviv Medical Program can include HBOT, along with cognitive training, dietary coaching, and physical performance training to help you recover even long after a stroke.
The program aims to offer patients a customized, coordinated, and multidisciplinary health plan to address their specific goals. As the aging process affects every person differently, each Aviv Clinics plan is individualized based on a patient’s post-stroke recovery needs.
Here’s how our process works:
- Assessment: Our dedicated team will conduct a thorough assessment to gain a holistic understanding of your health and craft a personalized health plan.
- Treatment: Under the supervision of Aviv’s medical staff, the treatment plan will entail a variety of health programs that are meant to get you on the road to recovery.
- Analysis: We will track data on how your treatment plan is progressing and make the necessary adjustments along the way.
- Follow-up: Upon conclusion of the treatment, our team will continue to follow up on your progress via an Aviv wearable device. This will allow us to send you reports on your health and performance.
Keren’s Inspiring Story
A holistic treatment plan that addresses the mind and body is key to successful recovery. Former Aviv Clinics patient Keren Trabelsi is a true testament to this fact.
Businesswoman and mother Keren Trabelsi suffered an ischemic stroke, causing paralysis on the left side of her body. Also, cognitive issues made daily tasks difficult, which did not make her feel as capable as she had been before. She sought the help of Aviv Clinics.
Now, 13 months later, she can walk comfortably, type with her left hand again, and engage in cognitive activities (i.e., crossword puzzles, Sudoku, etc.).
“[ Aviv Clinics is] like driving a Ferrari on the road to recovery versus driving like an old beaten-up car….”
Watch her post-stroke recovery story.
Stay current on our client success stories to learn more about what the Aviv Medical Program can help you achieve.
Is the Aviv Medical Program Right for You?
If you’ve been experiencing cognitive or physical challenges since your stroke, the Aviv Medical Program may be able to help. We have treated thousands of patients suffering from various conditions, enhancing their quality of life.
We encourage you to speak with one of our licensed medical staff to see if it’s right for you, as each person’s body, medical history, and circumstances differ. Our staff will take the time to understand your health history, symptoms, and goals. This process will help us determine whether the Aviv protocol is a good fit.
How Long Does It Take to See Results?
Improving physical and cognitive performance does not happen overnight. The Aviv Medical Program requires time and careful compliance to achieve success.
HBOT sessions take approximately two hours daily, five days a week, for 8-12 weeks. However, this timeline may vary across patients. Our clients see members of the Aviv healthcare team for additional therapies or coaching (e.g., cognitive training, dietary coaching, and physical performance training) multiple times each week.
Learn More about Post-Stroke Recovery
If you need help finding a stroke recovery plan, contact Aviv Clinics. Our diverse team of medical professionals is experienced in crafting customized treatment plans that have brought significant and fulfilling results for our patients.
Improving your quality of life begins here.
Hyperbaric Oxygen Therapy Induces Cognitive Function: New Study Shows
In the past hundred years, life expectancy has risen from 55 to 80. A critical focus of medicine and healthcare in general, innovative drug therapies, medical devices, and other aspects of modern diagnostic, treatment, and recovery have all played a role in this. The emphasis is now shifting to extending ‘healthspan’ to match lifespan. There are, of course, limits to the physical capabilities of the body but one vital organ, traditionally associated with modern treatment, is proving highly responsive to new therapies. Brain functions can not only be kept from decline but even improved.
Lifestyle changes, specifically diet, physical and mental exercise, have long been recognized to increase cognitive function as we get older. Foods, fitness machines and applications abound explicitly aimed for the older generation. But the elixir of a drug or other therapies that significantly fight age-linked cognitive decline has so far proved elusive.
A recently published study by researchers from Israel has shown that Hyperbaric Oxygen Therapy (HBOT) is emerging as an essential therapy in reversing an age-related decline in cognitive function.
HBOT as an enhancer of brain function
Dr Shai Efrati, Dr Amir Hadanny and a team at the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, lead researchers of a new study published in the peer-review journal, Aging, demonstrated the benefits of an HBOT therapeutic protocol created at the Shamir Medical Center.
The study was a collaboration between the Sackler School of Medicine and Sagol School of Neuroscience at Tel Aviv University.
The study was the first controlled clinical and randomized trial exploring the effect of HBOT on cognitive functions in fit ageing adults. It determined that HBOT was especially beneficial for the participants in improving comprehensive cognitive functions: attention, information processing speed and executive functions.
HBOT is emerging as an essential therapy in reversing an age-related decline in cognitive function.
HBOT’s role in reversing Age-Related Cognitive Decline
Dr Efrati issued a statement marking the publication of the study, in which he underlines the consequences and concerns related to decline in cognitive and functional ability in highly-developed societies:
“Major research efforts around the world are focused on improving the cognitive performance of the so-called ‘normal’ ageing population,” Dr Efrati said. “In our study, for the first time in humans, we have found an effective and safe medical intervention that can address this unwanted consequence of our age-related deterioration.”
Dr Hadanny added the treatment has now been in use for several years and scientists have begun to comprehend how brain function can be restored with HBOT.
“In the past, we have demonstrated HBOT’s potential to improve/treat brain injuries such as stroke, traumatic brain injury and anoxic brain injury (due to sustained lack of oxygen supply) by increasing brain blood flow and metabolism,” Dr Hadanny concluded: “This landmark research could have a far-reaching impact on the way we view the ageing process and the ability to treat its symptoms.”
Mechanism of Hyperbaric Oxygen Therapy
Though the brain accounts for only 2% of body mass, it utilizes over 20% of an individual’s oxygen intake, much of the cause of a decline in physical and cognitive functioning can be ascribed to a decrease in efficiency of oxygen processing associated with ageing.
The HBOT protocol targets this problem by placing patients in a pressurized suite where they breathe 100% oxygen. This raised oxygen in the body tissue by between 10 to 15 times above normal. Not only do overall oxygen levels increase, but the fluctuations in the oxygen levels in the body leads to the release of growth factors and stem cells that promote healing.
Conclusions on oxygen and brain function
The study enrolled sixty-three healthy, vigorous adults who were subjected to HBOT for two hours a day, five days a week, for three months. Their cognitive function was measured by using a comprehensive series of computerized cognitive appraisals. Cerebral blood flow was quantified by using a magnetic resonance imaging technique that observes the journey blood takes through the organs and tissues, known as brain perfusion.
Amongst the essential conclusions of the analysis was the correlation between the above-noted improvements and cerebral blood flow to different areas of the brain.
The study swells the mass of data regarding the efficacy of HBOT in generating brain function. Noticeably, the combination of pure oxygen and higher pressure led to increases in tissue oxygenation whilst simultaneously focusing on pressure-sensitive genes. Combined, this enhanced and restored tissue metabolism. This was the first time that such benefits had been observed in healthy patients as previous studies had focused on patients with cerebral impairments due to a range of conditions.
HBOT and reversal of Cognitive Decline in ageing
The improvements noted in the participants’ attention and cognitive processing speeds, possibly because of amplified blood flow to the brain. HBOT enhanced cerebral blood flow and regenerate brain cells and blood vessels in individuals with no brain damage. Previous studies had concentrated on the benefits to post-stroke, traumatic and anoxic brain injury
These improvements in overall cognitive function were still observable six months after treatment, Dr Efrati, writing in Psychology Today, proposed that the technique might even reverse damaged brain tissue. He further noted that this would be the first time an effective medical intervention had been observed to reverse age-related cognitive decline.
“Most drugs and interventions are at best slowing the expected decline,” he said. “For the first time in humans, we have discovered a way to regenerate the ageing brain — as can be seen by brain MRI — and enable us to gain back the cognitive function of our younger selves.”
The Aviv Clinics at The Villages, Florida, is now using this research based protocol. To learn more contact the clinic: click here.
Breakthrough Study Shows Hyperbaric Oxygen Treatments Helps Stop Biological Aging
A landmark study from researchers in Israel has found that hyperbaric oxygen therapy (HBOT) improves two key biological signs of aging in humans – the first study to ever make this finding. The research shows it’s possible to target the aging process at the basic cellular-biological level. This breakthrough in biology of aging research provides scientists a new foundation for investigating ways to slow the aging process.
Published in the peer-reviewed journal Aging, the study involved patients aged 64 and older who went through a series of HBOT treatments. Blood tests taken over the course of the study showed hyperbaric oxygen treatment improved two common signs of biological aging – a shortening of telomeres on chromosomes and the accumulation of senescent cells.
The significance of this is difficult to overstate. Telomeres are nucleotide sequences that protect the ends of chromosomes from deterioration or fusion with other chromosomes. A shortening in their length of about 20 to 40 bases per year is associated with serious life-threatening illnesses. Stopping and reversing telomere shortening has long been considered a key to slowing biological aging.
Senescent cells inhibit cell proliferation. The accumulation of senescence cells contributes to age-associated conditions and illnesses. Eliminating them can improve those conditions and illnesses, according to past animal studies.
The “Holy Grail” of the Biology of Aging
The new study is part of an ongoing comprehensive aging research program in Israel. A previous study, released earlier in 2020, showed that HBOT also improves cognitive function.
“After dedicating our HBOT research to exploring its impact on the areas of brain functionality and age-related cognitive decline, we have now uncovered for the first time in humans HBOT’s biological effects at the cellular level in healthy aging adults,” Dr. Shai Efrati, director of the Sagol Center for Hyperbaric Medicine and Research at the Yitzhak Shamir Medical Center and a co-author on the study, said in a news release.
Efrati called telomere shortening “the ‘Holy Grail’ of the biology of aging” and noted that researchers are exploring many pharmacological and environmental interventions in the hope of enabling telomere elongation.
“The significant improvement of telomere length shown during and after these unique HBOT protocols provides the scientific community with a new foundation of understanding that aging can, indeed, be targeted and reversed at the basic cellular-biological level,” said Efrati, who also holds an associate professor position at the Sackler Faculty of Medicine and the Sagol School of Neuroscience at Tel Aviv University.
How The Study Was Conducted
Efrati co-authored the study with Dr. Amir Hadanny, Chief Medical Research Officer of The Sagol Center for Hyperbaric Medicine and Research. The two focused on testing the impact of HBOT on telomere length and senescent cell concentrations in a non-pathological, aging adult population.
Efrati and Hadanny conducted the prospective trial with 35 healthy, independent adults. None of the patients made any changes to their lifestyle, diet or medication during the study. Each received 60 daily HBOT sessions over the course of 90 days.
Whole blood samples were collected before treatment and again at the 30th and 60th session. Their blood was checked again one to two weeks following the last HBOT session to assess peripheral blood mononuclear cells (PMBCs) telomere length and senescence.
The study found that certain HBOT protocols induced regenerative effects.
Some telomeres increased by more than 20% in length, while senescent cells decreased in number by as much as 37%.
Dr. Hadanny said the pioneering study has
“opened the door for further research on the prolonged cellular impact of HBOT to reverse the aging process.”
He said that up until the study, only lifestyle modifications and intense exercise showed the ability to slow telomere length shortening.
“What is remarkable to note in our study is that in just three months of HBOT, we were able to achieve such significant telomere elongation – at rates far beyond any of the current available interventions or lifestyle modifications,” said Dr. Hadanny.
Dr. Efrati is medical advisor to Aviv Scientific LTD, which offers HBOT treatments, cognitive and physical training and nutritional coaching to enhance brain and body performance at the Aviv Clinic at the Center for Advanced Healthcare at Brownwood in The Villages. For more information, or to schedule a consultation, contact the clinic.