Research on Chronic Wounds and HBOT
This section contains medical information and is intended for healthcare professionals only.
Back to client websiteWound Treatment
Hyperbaric oxygen therapy (HBOT) offers professionals a more robust, evidence-based healing pathway for patients struggling with difficult-to-heal wounds. HBOT can serve as a valuable adjunct in treating chronic and non-healing wounds, like diabetic ulcers, radiation-induced injuries, and compromised flaps or surgical sites. HBOT significantly enhances tissue oxygenation, supporting growth factor release, angiogenesis, and collagen synthesis critical for repair. Evidence from systematic reviews demonstrates that HBOT reduces amputation risk in diabetic foot ulcers and improves healing rates in refractory wounds. HBOT is also a recognized therapy for radiation injuries, thermal burns, skin graft compromise, and trauma-related wounds.
Data and Studies from The Sagol Center
- Hyperbaric oxygen therapy for nonhealing vasculitic ulcers
Clinical and Experimental Dermatology, January 2007, 32(1), 12-17
- Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy
Advances in Skin & Wound Care, December 2016, 29(12), 560-566
More Studies
- Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy
The Journal of Rheumatology, August 2006, 33(8), 1694-1696
- Systematic review and meta-analysis of clinical trials examining the effect of hyperbaric oxygen therapy in people with diabetes-related lower limb ulcers
Diabetic Medicine, July 2019, 36(7), 787-917
- Hyperbaric oxygen therapy: Antimicrobial mechanisms and clinical application for infections
Biomedicine & Pharmacotherapy, January 2019, 109, 440-447
- Effect of hyperbaric oxygen therapy on the patients with venous leg ulcer: A systematic review and meta-analysis
Asian Journal of Surgery, 2023, 46(10), 4131-4137