This section contains medical information and is intended for healthcare professionals only.Back to client website
Cognitive Performance and Aging
Age-related cognitive and functional decline has become a significant concern in the Western world. More than half of community-dwelling individuals, sixty years, and older, express concern about declining physical and cognitive abilities. Major research efforts around the world are focused on improving cognitive performance of the so-called 'normal' aging population. Over years of research, there is growing evidence from clinical studies that HBOT, utilized in a repeated daily sessions protocol, has neurotherapeutic effects which can improve and restore cognitive brain functions.
Data and Studies from The Sagol Center
Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial
Aging. June 26, 2020
Hyperbaric Oxygen Therapy Ameliorates Pathophysiology of 3xtg-Ad Mouse Model by Attenuating Neuroinflammation
Neurobiol Aging 62 (Feb 2018): 105-19.
Hyperbaric Oxygen Therapy as a New Treatment Approach for Alzheimer’s Disease
Neural Regen Res 13, no. 5 (May 2018): 817-18.
The Hyperoxic-Hypoxic Paradox
Biomolecules. June 25, 2020
Hyperbaric oxygen therapy induces transcriptome changes in elderly: a prospective trial
Aging. November 24, 2021
Hyperbaric Oxygen Treatment – From Mechanisms to Cognitive Improvement
Biomolecules, 2021 Oct 15
Hyperbaric Oxygen Treatment: Effects on Mitochondrial Function and Oxidative Stress
Biomolecules, 2021, December 3
Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial
Aging. November 18, 2020
Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients
Aging. September 9, 2021
The effect of hyperbaric oxygen therapy on the pathophysiology of skin aging: a prospective clinical trial
Aging, September 16, 2021
Hyperbaric Oxygen Therapy for Alzheimer’s Dementia with Positron Emission Tomography Imaging: A Case Report
Med Gas Res 8, no. 4 (Oct-Dec 2018): 181-84.
Protective Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Patients with Vascular Dementia
Cell Transplant 28, no. 8 (Aug 2019): 1071-75.
Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via P38 Mitogen-Activated Protein Kinase in a Rat Model
Yonsei Med J 58, no. 1 (Jan 2017): 131-38.
Cognitive Enhancement of Healthy Young Adults with Hyperbaric Oxygen: A Preliminary Resting-State Fmri Study
Clin Neurophysiol 126, no. 11 (Nov 2015): 2058-67.
Chronic Intermittent Hypoxia/Reoxygenation Facilitate Amyloid-Beta Generation in Mice
J Alzheimers Dis 37, no. 2 (2013): 325-33.
Hyperoxygenation Effect on Cognitive Functioning in the Aged
N Engl J Med 281, no. 14 (Oct 2 1969): 753-7.